LNPs don't "get lost in the fat", they attach to whatever cell membranes they come into contact with. And the presence of arterial plaque will have zero effect on their ability to bond to ACE2 receptors in vascular endothelium. Arterial plaque is only ever present in lesions representing a tiny part of the interior surface of the larger …
LNPs don't "get lost in the fat", they attach to whatever cell membranes they come into contact with. And the presence of arterial plaque will have zero effect on their ability to bond to ACE2 receptors in vascular endothelium. Arterial plaque is only ever present in lesions representing a tiny part of the interior surface of the larger arteries. It does NOT line the arteries like clogged plumbing pipes! So your imagery doesn't work.
LNPs don't "get lost in the fat", they attach to whatever cell membranes they come into contact with. And the presence of arterial plaque will have zero effect on their ability to bond to ACE2 receptors in vascular endothelium. Arterial plaque is only ever present in lesions representing a tiny part of the interior surface of the larger arteries. It does NOT line the arteries like clogged plumbing pipes! So your imagery doesn't work.