Absolutely, I see two major factors contributing to injury and death:
amyloid plaque and oxidative stress.
https://outraged.substack.com/p/short-summary
https://outraged.substack.com/p/treatment-in-practice
https://outraged.substack.com/p/causes-of-injuries-and-deaths-from - With more information on amyloids:
So, the presence of toxic graphene can cause amyloidosis. However, if the technology used in these injections is also based on peptides (as has been widely reported in the scientific literature: Self-assembling peptide semiconductors | https://www.science.org/doi/10.1126/science.aam9756), the production of amyloid in the bone marrow can lead to severe amyloidosis and related complications and death, including the currently manifested so-called sudden death syndrome. The key question, therefore, is also what technology was used in these injections.
“Short peptides, specifically those containing aromatic amino acids, can self-assemble into a wide variety of supramolecular structures that are kinetically or thermodynamically stable; the representative models are diphenylalanine and phenylalanine-tryptophan. Different assembly strategies can be used to generate specific functional organizations and nanostructural arrays, resulting in finely tunable morphologies with controllable semiconducting characteristics. Such strategies include molecular modification, microfluidics, coassembly, physical or chemical vapor deposition, and introduction of an external electromagnetic field (EMF).
Self-assembling peptide nanomaterials may serve as an alternative source for the semiconductor industry because they are eco-friendly, morphologically and functionally flexible, and easy to prepare, modify, and dope. Moreover, the diverse bottom-up methodologies of peptide self-assembly facilitate easy and cost-effective device fabrication, with the ability to integrate external functional moieties. For example, the coassembly of peptides and electron donors or acceptors can be used to construct n-p junctions, and vapor deposition technology can be applied to manufacture custom-designed electronics and chips on various substrates.
The inherent bioinspired nature of self-assembling peptide nanostructures allows them to bridge the gap between the semiconductor world and biological systems, thus making them useful for applications in fundamental biology and health care research. Short peptide self-assemblies may shed light on the roles of protein semiconductivity in physiology and pathology. For example, research into the relationship between the semiconductive properties of misfolded polypeptides characteristic of various neurodegenerative diseases and the resulting symptoms may offer opportunities to investigate the mechanisms controlling such ailments and to develop therapeutic solutions. Finally, self-assembling short peptide semiconductors could be used to develop autonomous biomachines operating within biological systems. This would allow, for example, direct, label-free, real-time monitoring of a variety of metabolic activities, and even interference with biological systems.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457452/ “Peptide based nano-assemblies with their self-organizing ability has shown lot of promise due to their high degree of thermal and chemical stability, for biomaterial fabrication. Developing an effective way to control the organization of these structures is important for fabricating application-oriented materials at the molecular level. The present study reports the impact of electric and magnetic field-mediated perturbation of the self-assembly phenomenon, upon the chemical and structural properties of diphenylalanine assembly. Our studies show that, electric field effectively arrests aggregation and self-assembly formation, while the molecule is allowed to anneal in the presence of applied electric fields of varying magnitudes, both AC and DC. The electric field exposure also modulated the morphology of the self-assembled structures without affecting the overall chemical constitution of the material. Our results on the modulatory effect of the electric field are in good agreement with theoretical studies based on molecular dynamics reported earlier on amyloid forming molecular systems.”
“In last decade, there has been an increased focus on organic and bio-organic nano-assemblies. Peptide nanotubes, their physical properties, and assembly morphologies are extensively studied due to their excellent biocompatibility as well as functional and structural diversity. Many ordered supramolecular structures have been constructed using peptides as the building blocks. The most extensively utilized peptide-based building block is diphenylalanine (Phe-Phe or FF), which is the shortest bio-molecule known to self-assemble into ordered nanostructures. FF incidentally is also the core recognition motif of the β-amyloid polypeptide, a peptide associated with Alzheimer’s disease1. It can self-assemble into a variety of structures like microtubes, nanotubes2, microcrystals, nanofibers3, nanorods4, 5 and nanowires6.”
“The potential of these supramolecular structures have been utilized in diverse fields including nanofabrication, drug delivery vehicles7, bio-sensing8, energy storage devices, and hydrogels for tissue engineering”.
“One of the key challenges in the field of supramolecular chemistry has been controlling the self-assembly of molecules into ordered functional units. Previously, a number of strategies including pH mediated control21, 22, solvent mediated control23, covalent modifications24, vapour deposition25, 26, temperature27, surface28, 29, relative humidity30, symmetry31 and magnetite coating on the surface of nanotubes32 have been employed to regulate the architecture of diphenylalanine self-assemblies.”
Andrij Baumketner in a recent study, explored the feasibility of using external electric field to disaggregate amyloid fibrils, by inducing folding into an α-helical state reducing their β sheet conformation38. This is especially important because FF is the core recognition motif of β-amyloid segment. Here in this study, we attempt to confirm the effect of AC (Alternating Current) and DC (Direct Current) electric field on diphenylalanine self-assembly using experimental approach.
Different assembly strategies can be used to generate specific functional organizations and nano structural arrays, resulting in finely tunable morphologies with controllable semiconducting characteristics. Such strategies include molecular modification, microfluidics, subassembly, physical or chemical vapor deposition, and introduction of an external electromagnetic field.
Absolutely, I see two major factors contributing to injury and death:
amyloid plaque and oxidative stress.
https://outraged.substack.com/p/short-summary
https://outraged.substack.com/p/treatment-in-practice
https://outraged.substack.com/p/causes-of-injuries-and-deaths-from - With more information on amyloids:
The mere presence of toxic graphene, and similar components, can cause amyloidosis.
Amyloidosis is also a common complication after Covid-19 injections, as also confirmed by Pfizer documents listing various types of amyloidosis as possible post-vaccination complications in a Postmarketing Experience document: https://phmpt.org/wp-content/uploads/2021/11/5.3.6-postmarketing-experience.pdf
Amyloid arthropathy;
Amyloidosis;
Amyloidosis senile;
Cardiac amyloidosis;
Cerebral amyloid angiopathy;
Cutaneous amyloidosis;
Dialysis amyloidosis;
Gastrointestinal amyloidosis;
Hepatic amyloidosis;
Primary amyloidosis;
Pulmonary amyloidosis;
Renal amyloidosis;
Secondary amyloidosis;
Tongue amyloidosis; (“Covid tongue”)
So, the presence of toxic graphene can cause amyloidosis. However, if the technology used in these injections is also based on peptides (as has been widely reported in the scientific literature: Self-assembling peptide semiconductors | https://www.science.org/doi/10.1126/science.aam9756), the production of amyloid in the bone marrow can lead to severe amyloidosis and related complications and death, including the currently manifested so-called sudden death syndrome. The key question, therefore, is also what technology was used in these injections.
“Short peptides, specifically those containing aromatic amino acids, can self-assemble into a wide variety of supramolecular structures that are kinetically or thermodynamically stable; the representative models are diphenylalanine and phenylalanine-tryptophan. Different assembly strategies can be used to generate specific functional organizations and nanostructural arrays, resulting in finely tunable morphologies with controllable semiconducting characteristics. Such strategies include molecular modification, microfluidics, coassembly, physical or chemical vapor deposition, and introduction of an external electromagnetic field (EMF).
Self-assembling peptide nanomaterials may serve as an alternative source for the semiconductor industry because they are eco-friendly, morphologically and functionally flexible, and easy to prepare, modify, and dope. Moreover, the diverse bottom-up methodologies of peptide self-assembly facilitate easy and cost-effective device fabrication, with the ability to integrate external functional moieties. For example, the coassembly of peptides and electron donors or acceptors can be used to construct n-p junctions, and vapor deposition technology can be applied to manufacture custom-designed electronics and chips on various substrates.
The inherent bioinspired nature of self-assembling peptide nanostructures allows them to bridge the gap between the semiconductor world and biological systems, thus making them useful for applications in fundamental biology and health care research. Short peptide self-assemblies may shed light on the roles of protein semiconductivity in physiology and pathology. For example, research into the relationship between the semiconductive properties of misfolded polypeptides characteristic of various neurodegenerative diseases and the resulting symptoms may offer opportunities to investigate the mechanisms controlling such ailments and to develop therapeutic solutions. Finally, self-assembling short peptide semiconductors could be used to develop autonomous biomachines operating within biological systems. This would allow, for example, direct, label-free, real-time monitoring of a variety of metabolic activities, and even interference with biological systems.
Amyloid self-assembling peptides: Potential applications in nanovaccine engineering and biosensing https://onlinelibrary.wiley.com/doi/10.1002/pep2.24095
Peptide Semiconductor Times Are Coming | Nature Portfolio Bioengineering Community https://bioengineeringcommunity.nature.com/posts/37570-peptide-semiconductor-times-are-coming
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457452/ “Peptide based nano-assemblies with their self-organizing ability has shown lot of promise due to their high degree of thermal and chemical stability, for biomaterial fabrication. Developing an effective way to control the organization of these structures is important for fabricating application-oriented materials at the molecular level. The present study reports the impact of electric and magnetic field-mediated perturbation of the self-assembly phenomenon, upon the chemical and structural properties of diphenylalanine assembly. Our studies show that, electric field effectively arrests aggregation and self-assembly formation, while the molecule is allowed to anneal in the presence of applied electric fields of varying magnitudes, both AC and DC. The electric field exposure also modulated the morphology of the self-assembled structures without affecting the overall chemical constitution of the material. Our results on the modulatory effect of the electric field are in good agreement with theoretical studies based on molecular dynamics reported earlier on amyloid forming molecular systems.”
“In last decade, there has been an increased focus on organic and bio-organic nano-assemblies. Peptide nanotubes, their physical properties, and assembly morphologies are extensively studied due to their excellent biocompatibility as well as functional and structural diversity. Many ordered supramolecular structures have been constructed using peptides as the building blocks. The most extensively utilized peptide-based building block is diphenylalanine (Phe-Phe or FF), which is the shortest bio-molecule known to self-assemble into ordered nanostructures. FF incidentally is also the core recognition motif of the β-amyloid polypeptide, a peptide associated with Alzheimer’s disease1. It can self-assemble into a variety of structures like microtubes, nanotubes2, microcrystals, nanofibers3, nanorods4, 5 and nanowires6.”
“The potential of these supramolecular structures have been utilized in diverse fields including nanofabrication, drug delivery vehicles7, bio-sensing8, energy storage devices, and hydrogels for tissue engineering”.
“One of the key challenges in the field of supramolecular chemistry has been controlling the self-assembly of molecules into ordered functional units. Previously, a number of strategies including pH mediated control21, 22, solvent mediated control23, covalent modifications24, vapour deposition25, 26, temperature27, surface28, 29, relative humidity30, symmetry31 and magnetite coating on the surface of nanotubes32 have been employed to regulate the architecture of diphenylalanine self-assemblies.”
Andrij Baumketner in a recent study, explored the feasibility of using external electric field to disaggregate amyloid fibrils, by inducing folding into an α-helical state reducing their β sheet conformation38. This is especially important because FF is the core recognition motif of β-amyloid segment. Here in this study, we attempt to confirm the effect of AC (Alternating Current) and DC (Direct Current) electric field on diphenylalanine self-assembly using experimental approach.
Different assembly strategies can be used to generate specific functional organizations and nano structural arrays, resulting in finely tunable morphologies with controllable semiconducting characteristics. Such strategies include molecular modification, microfluidics, subassembly, physical or chemical vapor deposition, and introduction of an external electromagnetic field.
When it comes to Dr. Cole, I trust Dr. Mihalcea:
https://anamihalceamdphd.substack.com/p/you-cant-find-what-you-are-not-looking?utm_source=post-email-title&publication_id=956088&post_id=90239968&isFreemail=true&utm_medium=email