I believe I made some kind of distinction twixt minerals and other supplements - but I'll repeat, with better clarity. All molecules get broken down by digestive enzymes. Sometimes, taken orally, these molecules can get past the digestive enzymes in your mouth and get into the capillaries in the mouth - we see this with sublingual and Bu…
I believe I made some kind of distinction twixt minerals and other supplements - but I'll repeat, with better clarity. All molecules get broken down by digestive enzymes. Sometimes, taken orally, these molecules can get past the digestive enzymes in your mouth and get into the capillaries in the mouth - we see this with sublingual and Buccal. If not, they all get destroyed by digestive enzymes. The vitamins, proteins and AAs and fats however will get destroyed either by digestive enzymes or defense mechanisms in the blood - the immune system does this to foreign/alien matter.
But, even if the molecule is spared, which they aren't, they still don't know where to go. They don't know to go to cells, to breach cells and fit into the matrix. No. We make our own nutrients from scratch - those are made in cells and those are the only useful nutrients (vitamins, proteins, AAs, fats etc.).
As quite as it's kept, we make our own vitamin C, we have pathways that allow for self synthesis of ascorbic acid and it's many co factors. Exogenous C is of zero use to us.
Minerals are hyper catalytic, and to take some concentrate of a mineral is all kinds of dangerous. Just have some fresh raw food. All whole foods have minerals in them - even fresh spring or river water.
"All molecules get broken down by digestive enzymes".
That is absurd. Fats get broken down by lipases, proteins by proteases, and starches by amylase.
If vitamins were broken down by enzymes we would all be dead because we wouldn't get any from food. Blood levels of vitamins, including vitamin C!, can be very accurately measured to characterize the absorption profile.
You obviously have no idea what you are talking about— probably a dumb AI bot!
What you have to learn, and I can teach you all this (I teach Chem and Bio) is that so much science understandings that we know - is from yesteryear. All the science many know is from era in the past where little was truly understood - and one main reason was technology - we didn't have the tech. We simply did not have the technology faith 100 years ago, 50 years ago, and certainly not 300 years ago in the pirate age when we first had an idea about vitamin C.
Microscopes were all we had. Microscopes could only work in a petri dish, in a lab. And back then even the microscopes were crude. Today, 2023, we still don't have the tech to see and know what is going on inside a live human body, in real time. We are just know, with Single Molecule Science (SMS) beginning to learn what is happening inside cells - inside live cells, but still not live cells inside living organisms.
So much from yesteryear was conjecture, was extrapolations from degrees of plausibility. Assumptions bassically, assumptions that over the years, decades, calcified into gospel, "facts".
They are not facts but just still assumptions.
What we do know today - is that ascorbic acid, vitamin C, is hyper fragile. Even exposed to light and oxygen it is undone, not a little undone but all undone. A molecule needs to be fully intact in order for it to do anything, in order for it to be any kind of available biologically.
This for all molecules, all nutrient molecules. When we also know today, is that we make our own proteins from scratch, we also make our own essential amino acids like Leucine, Lysine, threonine etc.
Science of this century has also acknowledged pathways to show how humans synthesize ascorbic acid - from scratch.
As for fats - we already know that each and every fat in the body, we make from scratch. From ketones to cholesterol, like all animals and plants, we make our own.
If you don't believe humans have the ability to synthesize anything, consider those who fast. I study long term fasters - those who fast for ten days, 20, 30, 40 and 50 day fasts - water fasts.
While they all lose caloric weight, their body are still always synthesizing C, proteins, amino acids A, B12, etc.
Or, consider the woman. She can synthesize whole humans - from beyond scratch, From atoms, from a collection of atoms the woman makes another human.
Also understand the the point of digestion, and the immune system, is to destroy so much that enters the body. This idea that fat breaks down only so far, or proteins only break down so far, first of all, has never been witnessed in real time in a real human, and second, there is no factory inside the body that is sorting out the food we eat and like some conveyor belt factory, cleaving fats and proteins into the "Parts we need".
You are absolutely correct that much of what is taught in school is very outdated. In the area of medicine, what is learned in the lab can take fifteen or even twenty years to "filter down" into clinical practice. Most people's grasp of physics is what they learned back in 9th grade, and mostly Newtonian. Concepts like "non-locaity" and quantum entanglement are completely foreign. And completely new things are being discovered all the time, but there is such a time lag before it becomes widely known. I wonder how many doctors know about the glymphatic system yet? Or what the glycocaylyx is? The general public doesn't!
I does look as though a small percentage of humans can synthesize some ascorbate, but most WILL sucumb to Scurvy if none is supplied in the diet. The historical record about deaths of sailors before the British navy mandated carrying citrus fruits is pretty clear about that. And they already knew Scurvy was a dietary deficiency for decades before the navy did anything about it!
Nevertheless, ascorbate can be consumed and it WILL appear in the blood shortly afterwards. You can't deny that.
"This idea that fat breaks down only so far, or proteins only break down so far, first of all, has never been witnessed in real time in a real human, . . . "
The digestive process has been studied in real time in living humans. Stomach contents have been extracted and analyzed. The process has been extensively studied. I don't get how you think it hasn't. And there ARE many nutrients that must be obtained from diet or they will not be available in sufficient quantities to maintain life. Countless humans have died of nutrient deficiencies. You must be aware of that, so how can you claim we don't obtain nutrients from diet? And that the molecules are destroyed during digestion. That is prima facie false.
Here's the thing about vitamin C - it only works with it;s cofactors. The co factors (about ten of them) work in complete and absolute tandem, in concert, with ascorbic acid. Ascorbic acid on it's own is useless.
And again, all who work with the actual molecule know it is hyper fragile, hyper unstable, uber labile. Just like the mRNA molecule - which needs to be encased in lipids for any chance to remain intact - but lipids also get destroyed by myriad factors, from heat, exposure to light and oxygen and of course digestive enzymes.
Scurvy is not at all related to Vitamin C. Pirates had all manner of C Laden foods - call foods contain Vitamin C, from fish, to meats, tubers, grains, corn, vegetables, fruits etc. So it wasn't lack of vitamin C on board that got pirates Sick. It was the horrible conditions of sea life back then, lack of fresh clean water - for anything, drinking or cleaning. Rats, roaches and other vermin aboard the vessels etc.
But most critically, was venereal diseases. Every port of call was met with plenty of whores - and even gay sex on those filthy ships.
What they had on board those ships, after days at sea, was plenty o pathogens. Modern day ships, have plenty of pathogens on board and the close proximity of humanity can lend to greater chances for epidemia. We often hear of large fun cruise ships having some kind of outbreak.
So, flash back to hundreds of years ago with pirates and other sea faring folk, in living conditions far less complimentary than we could imagine today (living in cramped, cold and damp, dirty confines), with no hot water to clean with and many times foul water for drinking and cleaning, brushing teeth wasn’t all the rage and flossing wasn’t a thing, with mice and rats on board along with bugs and maggots, on little sleep (3 to 4 hour rotations – in tiny bunk beds), motion sickness, duress, stress…
These things will lead to a host of sailor maladies, including again the whores at the various ports of call – syphilis was rampant back then. Not to mention Small Pox, Measles, Influenza and Typhus Fever. Yes, few mention, when writing about the history of scurvy, in the time of or during the Age of Exploration – between 1500 and 1800 – where “millions” of sea faring Europeans succumbed to scurvy, that this was also the Age of Diseases, historic plagues, that wiped out millions of Spaniards, French, Portuguese, Dutch, Italians, Scottish and British to name a few.
Lack of vitamin C was not at all the cause for scurvy, nor the cure. We have to more so recognize perhaps the role of citric acid and not ascorbic acid as having some curative powers over harmful bacteria. Sure, while an orange, kiwi, lemon or lime will have good amounts of vitamin C (ascorbic acid), in these particular fruits there are greater concentrates of citric acid – thus the distinction as “citrus fruits”.
Today we know that Citric acid shows an unexpected ability to enhance the antimicrobial power of a wide range of disinfectants and antibiotic agents. We know that citrate hugely improves the ability of antibiotics to kill or inhibit a wide range of bacterial species including antibiotic resistant strains.
What cofactors? Ascorbate enters the cell by itself via the glucose receptors.
Your comments about Scurvy do not match observed symptoms. It is quite distinct from any of those other diseases you mentioned. And sailors back then didn't have access to any of those vitamin C-containg foods you mentioned —most of them lived on things like preserved meats and hardtack and rum.
And citric acid is very weak compared to the hydrochloric acid of the stomach.
All foods have Vitamin C in them. Especially those foods they had on pirate ships - which were: potatoes, Carrots, Cabbage and beef, liver, and vegetables and even fruit to various types of sea food, and so many other things that the British and other sailors had on board including grains and nuts.
The other components, cofactors and co enzymes found in real Vitamin C (in real fruits, and vegetables and humans and animals) are: Rutin, Bioflavonoids (vitamin P), Factor K, Factor J, Factor P, Tyrosinase, Ascorbinogen, Ascorbic Acid. All of these work in vital and complete concert with each other to do all the things “vitamin C” in our bodies does.
No supplement pills or powders (or drinks) have all of this.
And even if some company decided to gather up all of these components, or synthesize them from scratch, that super high tech pill could still never ever mimic what the real vitamin C and all its co factors does that is already in your body, that you synthesized on your own – not even remotely. Nor could those molecules in your pill or powder once again, remain intact while being exposed to all manner of criteria which will invariably include, air/oxygen, sunlight/daylight, heat, and digestive enzymes, to name a few.
I never said citric acid was as strong as hydrochloric acid. ?? Two different acids - just like ascorbic acid is different. Ascorbic acid however is the most labile of all three.
By the way - the Rum you mentioned can also make you sick. Being sea sick and drunk is not a good combination.
I believe I made some kind of distinction twixt minerals and other supplements - but I'll repeat, with better clarity. All molecules get broken down by digestive enzymes. Sometimes, taken orally, these molecules can get past the digestive enzymes in your mouth and get into the capillaries in the mouth - we see this with sublingual and Buccal. If not, they all get destroyed by digestive enzymes. The vitamins, proteins and AAs and fats however will get destroyed either by digestive enzymes or defense mechanisms in the blood - the immune system does this to foreign/alien matter.
But, even if the molecule is spared, which they aren't, they still don't know where to go. They don't know to go to cells, to breach cells and fit into the matrix. No. We make our own nutrients from scratch - those are made in cells and those are the only useful nutrients (vitamins, proteins, AAs, fats etc.).
As quite as it's kept, we make our own vitamin C, we have pathways that allow for self synthesis of ascorbic acid and it's many co factors. Exogenous C is of zero use to us.
Minerals are hyper catalytic, and to take some concentrate of a mineral is all kinds of dangerous. Just have some fresh raw food. All whole foods have minerals in them - even fresh spring or river water.
"All molecules get broken down by digestive enzymes".
That is absurd. Fats get broken down by lipases, proteins by proteases, and starches by amylase.
If vitamins were broken down by enzymes we would all be dead because we wouldn't get any from food. Blood levels of vitamins, including vitamin C!, can be very accurately measured to characterize the absorption profile.
You obviously have no idea what you are talking about— probably a dumb AI bot!
What you have to learn, and I can teach you all this (I teach Chem and Bio) is that so much science understandings that we know - is from yesteryear. All the science many know is from era in the past where little was truly understood - and one main reason was technology - we didn't have the tech. We simply did not have the technology faith 100 years ago, 50 years ago, and certainly not 300 years ago in the pirate age when we first had an idea about vitamin C.
Microscopes were all we had. Microscopes could only work in a petri dish, in a lab. And back then even the microscopes were crude. Today, 2023, we still don't have the tech to see and know what is going on inside a live human body, in real time. We are just know, with Single Molecule Science (SMS) beginning to learn what is happening inside cells - inside live cells, but still not live cells inside living organisms.
So much from yesteryear was conjecture, was extrapolations from degrees of plausibility. Assumptions bassically, assumptions that over the years, decades, calcified into gospel, "facts".
They are not facts but just still assumptions.
What we do know today - is that ascorbic acid, vitamin C, is hyper fragile. Even exposed to light and oxygen it is undone, not a little undone but all undone. A molecule needs to be fully intact in order for it to do anything, in order for it to be any kind of available biologically.
This for all molecules, all nutrient molecules. When we also know today, is that we make our own proteins from scratch, we also make our own essential amino acids like Leucine, Lysine, threonine etc.
Science of this century has also acknowledged pathways to show how humans synthesize ascorbic acid - from scratch.
As for fats - we already know that each and every fat in the body, we make from scratch. From ketones to cholesterol, like all animals and plants, we make our own.
If you don't believe humans have the ability to synthesize anything, consider those who fast. I study long term fasters - those who fast for ten days, 20, 30, 40 and 50 day fasts - water fasts.
While they all lose caloric weight, their body are still always synthesizing C, proteins, amino acids A, B12, etc.
Or, consider the woman. She can synthesize whole humans - from beyond scratch, From atoms, from a collection of atoms the woman makes another human.
Also understand the the point of digestion, and the immune system, is to destroy so much that enters the body. This idea that fat breaks down only so far, or proteins only break down so far, first of all, has never been witnessed in real time in a real human, and second, there is no factory inside the body that is sorting out the food we eat and like some conveyor belt factory, cleaving fats and proteins into the "Parts we need".
You are absolutely correct that much of what is taught in school is very outdated. In the area of medicine, what is learned in the lab can take fifteen or even twenty years to "filter down" into clinical practice. Most people's grasp of physics is what they learned back in 9th grade, and mostly Newtonian. Concepts like "non-locaity" and quantum entanglement are completely foreign. And completely new things are being discovered all the time, but there is such a time lag before it becomes widely known. I wonder how many doctors know about the glymphatic system yet? Or what the glycocaylyx is? The general public doesn't!
I does look as though a small percentage of humans can synthesize some ascorbate, but most WILL sucumb to Scurvy if none is supplied in the diet. The historical record about deaths of sailors before the British navy mandated carrying citrus fruits is pretty clear about that. And they already knew Scurvy was a dietary deficiency for decades before the navy did anything about it!
Nevertheless, ascorbate can be consumed and it WILL appear in the blood shortly afterwards. You can't deny that.
"This idea that fat breaks down only so far, or proteins only break down so far, first of all, has never been witnessed in real time in a real human, . . . "
The digestive process has been studied in real time in living humans. Stomach contents have been extracted and analyzed. The process has been extensively studied. I don't get how you think it hasn't. And there ARE many nutrients that must be obtained from diet or they will not be available in sufficient quantities to maintain life. Countless humans have died of nutrient deficiencies. You must be aware of that, so how can you claim we don't obtain nutrients from diet? And that the molecules are destroyed during digestion. That is prima facie false.
Here's the thing about vitamin C - it only works with it;s cofactors. The co factors (about ten of them) work in complete and absolute tandem, in concert, with ascorbic acid. Ascorbic acid on it's own is useless.
And again, all who work with the actual molecule know it is hyper fragile, hyper unstable, uber labile. Just like the mRNA molecule - which needs to be encased in lipids for any chance to remain intact - but lipids also get destroyed by myriad factors, from heat, exposure to light and oxygen and of course digestive enzymes.
Scurvy is not at all related to Vitamin C. Pirates had all manner of C Laden foods - call foods contain Vitamin C, from fish, to meats, tubers, grains, corn, vegetables, fruits etc. So it wasn't lack of vitamin C on board that got pirates Sick. It was the horrible conditions of sea life back then, lack of fresh clean water - for anything, drinking or cleaning. Rats, roaches and other vermin aboard the vessels etc.
But most critically, was venereal diseases. Every port of call was met with plenty of whores - and even gay sex on those filthy ships.
What they had on board those ships, after days at sea, was plenty o pathogens. Modern day ships, have plenty of pathogens on board and the close proximity of humanity can lend to greater chances for epidemia. We often hear of large fun cruise ships having some kind of outbreak.
So, flash back to hundreds of years ago with pirates and other sea faring folk, in living conditions far less complimentary than we could imagine today (living in cramped, cold and damp, dirty confines), with no hot water to clean with and many times foul water for drinking and cleaning, brushing teeth wasn’t all the rage and flossing wasn’t a thing, with mice and rats on board along with bugs and maggots, on little sleep (3 to 4 hour rotations – in tiny bunk beds), motion sickness, duress, stress…
These things will lead to a host of sailor maladies, including again the whores at the various ports of call – syphilis was rampant back then. Not to mention Small Pox, Measles, Influenza and Typhus Fever. Yes, few mention, when writing about the history of scurvy, in the time of or during the Age of Exploration – between 1500 and 1800 – where “millions” of sea faring Europeans succumbed to scurvy, that this was also the Age of Diseases, historic plagues, that wiped out millions of Spaniards, French, Portuguese, Dutch, Italians, Scottish and British to name a few.
Lack of vitamin C was not at all the cause for scurvy, nor the cure. We have to more so recognize perhaps the role of citric acid and not ascorbic acid as having some curative powers over harmful bacteria. Sure, while an orange, kiwi, lemon or lime will have good amounts of vitamin C (ascorbic acid), in these particular fruits there are greater concentrates of citric acid – thus the distinction as “citrus fruits”.
Today we know that Citric acid shows an unexpected ability to enhance the antimicrobial power of a wide range of disinfectants and antibiotic agents. We know that citrate hugely improves the ability of antibiotics to kill or inhibit a wide range of bacterial species including antibiotic resistant strains.
What cofactors? Ascorbate enters the cell by itself via the glucose receptors.
Your comments about Scurvy do not match observed symptoms. It is quite distinct from any of those other diseases you mentioned. And sailors back then didn't have access to any of those vitamin C-containg foods you mentioned —most of them lived on things like preserved meats and hardtack and rum.
And citric acid is very weak compared to the hydrochloric acid of the stomach.
All foods have Vitamin C in them. Especially those foods they had on pirate ships - which were: potatoes, Carrots, Cabbage and beef, liver, and vegetables and even fruit to various types of sea food, and so many other things that the British and other sailors had on board including grains and nuts.
The other components, cofactors and co enzymes found in real Vitamin C (in real fruits, and vegetables and humans and animals) are: Rutin, Bioflavonoids (vitamin P), Factor K, Factor J, Factor P, Tyrosinase, Ascorbinogen, Ascorbic Acid. All of these work in vital and complete concert with each other to do all the things “vitamin C” in our bodies does.
No supplement pills or powders (or drinks) have all of this.
And even if some company decided to gather up all of these components, or synthesize them from scratch, that super high tech pill could still never ever mimic what the real vitamin C and all its co factors does that is already in your body, that you synthesized on your own – not even remotely. Nor could those molecules in your pill or powder once again, remain intact while being exposed to all manner of criteria which will invariably include, air/oxygen, sunlight/daylight, heat, and digestive enzymes, to name a few.
I never said citric acid was as strong as hydrochloric acid. ?? Two different acids - just like ascorbic acid is different. Ascorbic acid however is the most labile of all three.
By the way - the Rum you mentioned can also make you sick. Being sea sick and drunk is not a good combination.
Science is not static Faith.