There are many great comments here. I am offering one option, once again, supported by published papers, that may have been overlooked. It could be used in conjunction with other great ideas mentioned by your readers.
The below studies indicate ultrasound efficacy against blood clots. One found 20Khz optimal:
There are many great comments here. I am offering one option, once again, supported by published papers, that may have been overlooked. It could be used in conjunction with other great ideas mentioned by your readers.
The below studies indicate ultrasound efficacy against blood clots. One found 20Khz optimal:
Hong, Aaron S., Jang-Seong Chae, Stuart B. Dubin, Stephen Lee, Michael C. Fishbein, and Robert J. Siegel. “Ultrasonic Clot Disruption: An in Vitro Study.” American Heart Journal 120, no. 2 (August 1, 1990): 418–22. https://doi.org/10.1016/0002-8703(90)90088-F.
Nedelmann, Max, Christian Brandt, Felicitas Schneider, B. Martin Eicke, Oliver Kempski, Frank Krummenauer, and Marianne Dieterich. “Ultrasound-Induced Blood Clot Dissolution without a Thrombolytic Drug Is More Effective with Lower Frequencies.” Cerebrovascular Diseases 20, no. 1 (July 8, 2005): 18–22. https://doi.org/10.1159/000086122.
The full papers may be obtained from Anna's Archive.
There are other studies in addition. See references from above, and Google Scholar for more:
I am unaware of any applicable device that could be delivered with urgency, so to achieve this, you may need to improvise. Fabrication is easy, and can be done with inexpensive, quickly delivered, off the shelf components. As you have a degree in electrical engineering, I'm sure you could get this assembled in less than 30 min. If not, I'm sure you could find an engineering student to do it for a fee. If I was closer, I would offer to do it.
A sonic transducer for 19-20Khz (20Khz was optimal according to one paper above) with amplifier and eye coupling, can be quickly and easily made from the following off the shelf components that can be obtained from Amazon Prime. I recommend you order them, keeping the option open and within the window of opportunity, and then when they are delivered, decide whether or not you wish to use them:
The above apparatus will additionally emit a magnetic field (it is not a piezoelectric), which may differentiate movement between iron-containing red blood cells(.33% by weight), and surrounding tissue, and plasma that does not contain iron, in addition to the sonic effect.
There are many app options for generating a 19Khz sine wave on a computer, including SoX, Audacity, Pure Data, etc. There are likely apps that run on a phone that can do the same. I would recommend one with a traditional logorithmic-response volume control (virtually all of them) so that low power can be achieved. As the frequency of the transducer tops out at 19Khz according to the specs, I would use that as the target frequency.
Low power and time is recommended, and may be necessary to differentiate beneficial effects from adverse ones. You will have to use your intelligence and intuition in lieu of comprehensive, peer-reviewed studies.
actually its acoustic waves for kidney stones and gallstones. When being treated you can hear the pop, its not ultrasonic, its focused soundwaves traveling very fast. They have been shown to stimulate growth factor in injured tissues and have been studied and used for wound healing as well as muscle injuries and even cellulite breakdown and removal.
Steve:
There are many great comments here. I am offering one option, once again, supported by published papers, that may have been overlooked. It could be used in conjunction with other great ideas mentioned by your readers.
The below studies indicate ultrasound efficacy against blood clots. One found 20Khz optimal:
Hong, Aaron S., Jang-Seong Chae, Stuart B. Dubin, Stephen Lee, Michael C. Fishbein, and Robert J. Siegel. “Ultrasonic Clot Disruption: An in Vitro Study.” American Heart Journal 120, no. 2 (August 1, 1990): 418–22. https://doi.org/10.1016/0002-8703(90)90088-F.
Nedelmann, Max, Christian Brandt, Felicitas Schneider, B. Martin Eicke, Oliver Kempski, Frank Krummenauer, and Marianne Dieterich. “Ultrasound-Induced Blood Clot Dissolution without a Thrombolytic Drug Is More Effective with Lower Frequencies.” Cerebrovascular Diseases 20, no. 1 (July 8, 2005): 18–22. https://doi.org/10.1159/000086122.
The full papers may be obtained from Anna's Archive.
There are other studies in addition. See references from above, and Google Scholar for more:
https://scholar.google.com/scholar?hl=en&as_sdt=0%2C10&q=sonic+sound+blood+clot+dissolution+thrombosis&oq=sonic+sound+blood+clot+dissolution+throm
I am unaware of any applicable device that could be delivered with urgency, so to achieve this, you may need to improvise. Fabrication is easy, and can be done with inexpensive, quickly delivered, off the shelf components. As you have a degree in electrical engineering, I'm sure you could get this assembled in less than 30 min. If not, I'm sure you could find an engineering student to do it for a fee. If I was closer, I would offer to do it.
A sonic transducer for 19-20Khz (20Khz was optimal according to one paper above) with amplifier and eye coupling, can be quickly and easily made from the following off the shelf components that can be obtained from Amazon Prime. I recommend you order them, keeping the option open and within the window of opportunity, and then when they are delivered, decide whether or not you wish to use them:
Sonic transducer:
https://www.amazon.com/Generic-Surface-Conductor-Transducer-Exciter/dp/B00Y8ISYHG/ref=sr_1_1?crid=3M7J2W8BOKO3Z&dib=eyJ2IjoiMSJ9.3s-A2GfQEkIADOzw192sUg0uMY2wU8zmeITSUSFurmxlgq3PX-8TWu_CbZTD0eH8eOKPf9G1cTJEVrnUn7is0anlasgD7SGeELwiAQUejRg.qRC7rPpG6EgTniy28yqrcUOUravgw6x7FZAvZFdPELg&dib_tag=se&keywords=bone+conduction+transducer+with+wires+-+8+ohm+1+watt&qid=1722206069&sprefix=bone+conductor+transducer+with+wires+-+8+ohm+1+watt%2Caps%2C134&sr=8-1
or
https://www.amazon.com/Dayton-Audio-BCE-1-Conducting-Exciter/dp/B00HFG6AZG/ref=pd_bxgy_thbs_d_sccl_1/135-6747190-4650147?pd_rd_w=fIO34&content-id=amzn1.sym.c51e3ad7-b551-4b1a-b43c-3cf69addb649&pf_rd_p=c51e3ad7-b551-4b1a-b43c-3cf69addb649&pf_rd_r=1JHZ2WS6K8F1SSHGNQ6Q&pd_rd_wg=nxj2e&pd_rd_r=f0288234-84e1-454e-b7b2-929f4e18900d&pd_rd_i=B00HFG6AZG&psc=1
Amplifier:
https://www.amazon.com/Audio-Development-Tools-Adafruit-Amplifier/dp/B00PY2YSI4/ref=pd_bxgy_thbs_d_sccl_2/135-6747190-4650147?pd_rd_w=y8Dt8&content-id=amzn1.sym.c51e3ad7-b551-4b1a-b43c-3cf69addb649&pf_rd_p=c51e3ad7-b551-4b1a-b43c-3cf69addb649&pf_rd_r=4FBPGE0AY2TC4MB9892B&pd_rd_wg=Z021X&pd_rd_r=3383ddc5-70a4-4e1f-aa15-69dce70e7eb1&pd_rd_i=B00PY2YSI4&psc=1
Epoxy putty for the eye coupling:
https://www.amazon.com/J-B-Weld-8277-White-Pack/dp/B000BRQ0TW/ref=sr_1_3?crid=1BBDTXZJA9A10&dib=eyJ2IjoiMSJ9.A4h12qrc3anvGOoxLdw-ebnlJEnH2tsDAFwPD2VfNP8bL1ajTAGSpWwrBFH-d43-UMi9G605_lgaBZxfLyYKFkVVmyCOsgG0j45Lwx4MMBcURd3uuv3UWyPg9Gm3kCKfmE5Rnlmbk6i4WXgqS6Hsm9U7XLTyS8sSNNQtj2tFjp8cZFiVbh06DR8mb65V5orIQ_TAOLfqd8N0cWdr1S0LEpgx94Gcc_vDPJO27YyeCXs.0TGpnWgVPE_fqi-2Oc2b0opWxsnPTQHj1BIskbDudFk&dib_tag=se&keywords=epoxy%2Bputty&qid=1722206436&sprefix=expoxy%2Bputty%2Caps%2C114&sr=8-3&th=1
24mm steel ball to form putty based on eye diameter of 24mm:
https://www.amazon.com/uxcell-Stainless-Steel-Bearing-Precision/dp/B098S1FY9W/ref=sr_1_1?crid=3ELZKA7USK2UB&dib=eyJ2IjoiMSJ9.bx-bOLunlUNExj4VA6cmofX5uIYY1pYLFz313XFPP8SHkND7Xcobphu7SaT4PmWZDR70THQ2_iyu7h6wTxYK7ZVfdfSQfYiRQvk0KAiGtFwjqPsLCbP1WtRmRYfQi-fotX1cLYjZyXQk26ZOF4Dd-8Qqq-5xYxTqw9zE7KcdKPPG_C2bcr-b4IELYEI8B9iVZDi-1R1DaS2TsOm2YU8GSgpHNKJf7fjOvX0_3FO-Ll8.fRQNwgSq9miViVR72523lzuc2Y3cmL8tecGPWik1Hco&dib_tag=se&keywords=24mm%2Bball&qid=1722206673&sprefix=24mm%2Bball%2Caps%2C122&sr=8-1&th=1
latex gloves for expoxy shaping:
https://www.amazon.com/FifthPulse-Nitrile-Exam-Gloves-Blue/dp/B09SM4L7XJ/ref=sr_1_2?crid=CWQFOC2ST5K4&dd=6aDEA3QwcozHU2QfGzs9ndNGzeC2M1AGI-JCm90QnS4%2C&ddc_refnmnt=free&dib=eyJ2IjoiMSJ9.c3rWCG6_vuUkQrRqj4MBQdXyxbquYnRM4g0A97EaHf1L5sZtiWk73ciQEa3lYk7L-xTC92b7OhBiSxYTz7CcEMAWiQIdIWV4q_JB-TE236tnS4g3VgZG74aAEZgzwWQQ65HZ4wiqNVe1u_nfzwgy423ITjtDGBr45EXW9Z6w7oXLEWsarKWXvyhHgljSOPCLETbh3qvRSoJ9b0E55xBWQmkCz23Jpl8yFGOq6mP5MLniMLoPEE0C0cn3hguWyTvpLQ0wKH23hVGJre8ZFyGouHyBAbPHOb0vGcLDero6EOI.nOr8sAOvq5f0gatwjJ_8jXMpHEYeckQyo20BCcP6iUI&dib_tag=se&keywords=latex+gloves&qid=1722207045&refinements=p_101%3A19346686011&rnid=19346684011&sprefix=latex+gloves%2Caps%2C137&sr=8-2
Audio Cable:
https://www.amazon.com/AxcessAbles-Instrument-Minijack-6-35mm-Stereo/dp/B08CZQC981/ref=sr_1_4?crid=K4WSJGBKHQ56&dd=pazDgzac1UW7W_SWdsKDaA%2C%2C&dib=eyJ2IjoiMSJ9.gijpdzQK8-Uaz8YG6UjkHmzzP16qlhes10dCqJ-0Hn6gTxZ_DAKTcNb8Esrb8jGsbkxyMiXG6dohrQmsQM0fL9NwRdxq9EW-pqQCLGKhe6dYZrPZTOVzdUR7VVgsJzikqlm5g_hIt9inaOA09eAMjhFPrsR0XrLCy2mDW5NBXTSuSGLbmWpvg3md0mv2Kwxxr0BvumHTiTPyhaYOJ7V5L4hkTKVlcmrnCSyGLLuBsn0.oSC4Zi3YsCY_oqsmGhGnMUCG-EvsEOIaqeEAcq2yVsc&dib_tag=se&keywords=1%2F8+audio+cable&qid=1722207138&refinements=p_90%3A8308921011&rnid=8308919011&sprefix=1%2F8+audio+cable%2Caps%2C114&sr=8-4
Power cable for connecting amp to USB 5v supply:
https://www.amazon.com/LIANSUM-Universal-5-5x2-1mm-Connectors-3-5x1-35/dp/B094GZ8L2P/ref=sr_1_2?sr=8-2
The above apparatus will additionally emit a magnetic field (it is not a piezoelectric), which may differentiate movement between iron-containing red blood cells(.33% by weight), and surrounding tissue, and plasma that does not contain iron, in addition to the sonic effect.
There are many app options for generating a 19Khz sine wave on a computer, including SoX, Audacity, Pure Data, etc. There are likely apps that run on a phone that can do the same. I would recommend one with a traditional logorithmic-response volume control (virtually all of them) so that low power can be achieved. As the frequency of the transducer tops out at 19Khz according to the specs, I would use that as the target frequency.
Low power and time is recommended, and may be necessary to differentiate beneficial effects from adverse ones. You will have to use your intelligence and intuition in lieu of comprehensive, peer-reviewed studies.
Good luck.
It seems a very nice idea! Like ultrasound used for kidney stones and gallstones!
actually its acoustic waves for kidney stones and gallstones. When being treated you can hear the pop, its not ultrasonic, its focused soundwaves traveling very fast. They have been shown to stimulate growth factor in injured tissues and have been studied and used for wound healing as well as muscle injuries and even cellulite breakdown and removal.