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The bias associated with getting the first shot that seems to generate negative excess all-cause mortality (XACM) of which you speak is probably just the trained innate immunity triggered by the first dose that generates heterologous protection against most types of non-genetic disease. Here is a recent review on trained innate immunity and how it is the critical host defence against turbo cancers and pandemics [Laderoute MP. Trained Innate Immunity: Mechanisms & Meaning. February 10, 2025. https://hervk102.substack.com/p/trained-innate-immunity-mechanisms. ]. Trained innate immunity is also why using XACM underestimates the actual number of deaths such that for certain months there are more COVID-19 deaths than XACM deaths as reported by Dr. Denis Rancourt.

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